Glycerol is a naturally occurring chemical. People use it as a medicine. Some uses and dosage forms have been approved by the U.S. Food and Drug Administration (FDA).
Glycerol is taken by mouth for weight loss, improving exerciseperformance, helping the body replace water lost during diarrhea and vomiting, and reducing pressure inside the eye in people with glaucoma. Athletes also use glycerol to keep from becoming dehydrated.
Healthcare providers sometimes give glycerol intravenously (by IV) to reduce pressure inside the brain in various conditions including stroke,meningitis,encephalitis,Reye’s syndrome,pseudotumor cerebri, central nervous system (CNS) trauma, and CNS tumors; for reducing brain volume for neurosurgical procedures; and for treating fainting on standing due to poor blood flow to the brain (postural syncope).
Some people apply glycerol to the skin as a moisturizer.
Eye doctors sometimes put a solution that contains glycerol in the eye to reduce fluid in the cornea before an eye exam.
Rectally, glycerol is used as a laxative
Side Effects & Safety
Glycerol seems to be safe for most adults. When taken by mouth, glycerol can cause side effects including headaches,dizziness,bloating , nausea, vomiting, thirst, and diarrhea.
Glycerol may not be safe when injected intravenously (by IV). Red blood cells might get seriously damaged.
Specification of Glycerin :
Method
Specified Range
Typical values
Relative density 20 /20°C2
ISO 2099 (Part 2) : 1972
1.2623 min
1.2632
Refractive index n20D2
APAG-GL-006 : 1988
1.4731 min
1.4737
Glycerine content %1
APAG-GL-009 : 1988
99.5 min
99.8
Colour APHA1
ASTM D1209 : 1993
10 max
2.5
Fatty acids & esters 1(ml 0.5N NaOH/50g)
USP XXllI : 1995
1.0 max
0.14
Sulphated ash %2
USP XXllI : 1995
0.01 max
0.004
Chlorides ppm Cl2
USP XXllI : 1995
10 max
< 10
Heavy metals ppm Pb2
USP XXlIl (Mtd 1) : 1995
5 max
< 5
Chlorinated compounds ppm Cl2
USP XXllI : 1995
30 max
< 30
Arsenic ppm2
USP XXllI : 1995
1.5 max
< 1.5
Sulphate ppm2
USP XXllI : 1995
20 max
< 20
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