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White Birch bark extract BETULINIC ACID CAS 472-15-1

Chemical Name: BETULINIC ACID

Botanical Resource: Betula alba L.
CAS No.:
472-15-1

Molecular Formula:C30H48O3

Molecular weight: 456.7

Appearance: white crystalline powder

 

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Product Description 

Betulinic acid is a naturally occurring pentacyclic triterpenoid which has anti-retroviral, anti-malarial, and anti-inflammatory properties, as well as a more recently discovered potential as an anticancer agent, by inhibition of topoisomerase. It is found in the bark of several species of plants, principally the white birch (Betula pubescens) from which it gets its name.

Betulin also called the birch wood alcohol ester brain, belong to without rings triterpene compounds. Is tasted for white crystal powder, melting point of 248 ~ 251 °C (methanol-chloroform). Soluble in ethanol, ethyl ether, chloroform and benzene, slightly soluble in cold water, and petroleum ether, etc.

Function of Betulinic acid

1. Betulin can Adaptogenic and immunomodulating activities.
2. Betulin can Antioxidant and antihypoxic activities.
3. Betulin can Hepatoprotective, detoxic, hypolipidemic activities.
4. Betulin can Anti-inflammatory and antiallergic activity .
5. Betulin can Antimutagen and anticancer activities.
6. Betulin can Antiviral and antituberculous activity.
7. Betulin can Temoleptic activity.
8. Betulin can inhibits the activity of proteins dissolved in hair fibers, improves damaged hair luster, and promotes hair growth. 

Application of Betulinic acid

1.Birch Extract Betulinic Acid are Applied in pharmaveutical field, it is mainly used in treating bacterial infection, gastroenteritis and cardiovascular diseases.

2.Birch Extract Betulinic Acid are Applied in feed additive field, it is mainly used in feed additive for protecting the poultry, livestock and fishes against the disease.

3.Birch Extract Betulinic Acid are Applied in health product field, it is often made into capsule to lower blood pressure and blood-fat.

4.Birch Extract Betulinic Acid are Applied in food field, it is mainly as a functional food additives used in cookie, bread, meat products and so on.

CERTIFICATE  OF  ANALYSIS

ANALYSIS SPECIFICATION RESULTS METHOD&REFERENCE
Sieve Analysis100% pass 80 meshCompliesUSP<786>
Bulk density40-65g/100ml54g/100mlUSP<616>
Loss on Drying5% Max3.51%USP<731>
Sulphated Ash  5% Max3.27%USP<731>
Extract SolventAlcohol&WaterComplies 
Heavy Metal20ppm MaxCompliesAAS
Pb2ppm MaxCompliesAAS
As2ppm MaxCompliesAAS
Cd1ppm MaxCompliesAAS
Hg1ppm MaxCompliesAAS
Residual Solvents0.05% Max.NegativeUSP<561>
Microbiology
Total Plate Count10000/g MaxCompliesUSP30<61>
Yeast & Mold       1000/g MaxCompliesUSP30<61>
E.ColiNegativeCompliesUSP30<61>
Salmonella  NegativeCompliesUSP30<61>
Conclusion:    Conform with specification.
Storage:       In cool & dry place. Keep away from strong light and heat.
Shelf life:      2 years when properly stored.

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