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What Is Reserpine?

Reserpine is an alkaloid, derived from the roots of Rauwolfia serpentine and vomitoria, and an adrenergic uptake inhibitor with antihypertensive effects. Reserpine is lipid soluble and can penetrate blood-brain barrier. This agent binds and inhibits catecholamine pump on the storage vesicles in central and peripheral adrenergic neurons, thereby inhibiting the uptake of norepinephrine, dopamine serotonin into presynaptic storage vesicles.

This results in catecholamines and serotonin lingering in the cytoplasm where they are destroyed by intraneuronal monoamine oxidase, thereby causing the depletion of catecholamine and serotonin stores in central and peripheral nerve terminals. Depletion results in a lack of active transmitter discharge from nerve endings upon nerve depolarization, and consequently leads to a decreased heart rate and decreased arterial blood pressure as well as sedative effects.

English name: reserpine
CAS number: 50-55-5
Molecular Formula: C33H40N2O9
Molecular weight: 608.67900
Accurate quality: 608.27300
PSA: 117.78000
LogP: 4.10900
Appearance:Pale yellow powder

How to use Reserpine?

1.Uses of Reserpine.
2.It is used to treat high blood pressure.
3.It is used to treat schizophrenia.
4.It may be given to you for other reasons. Talk with the doctor.

How do I store and/or throw out Reserpine?

1.Store at room temperature.
2.Protect from light.
3.Store in a dry place. Do not store in a bathroom.
4.Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
5.Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

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