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Ceramide

2019-03-29

Ceramide ist eine Art Aminolipide bestehend aus langkettigen Basen und Fettsäuren sphingosine.Amide (Ceramide in Ceramide als das Skelett einer Klasse von Phospholipid, im Grunde haben Ceramide cholinphosphat und Ceramide Ethanolphosphat, Phospholipide sind die Hauptkomponenten der Zellmembran, Hornschicht in 40% ~ 50% von Talg besteht aus Ceramide, Ceramide is the main part of the intercellular matrix, in maintaining water balance plays an important role.
Ceramides powder are a family of waxy lipid molecules. A ceramide is composed of sphingosine and a fatty acid. Ceramides are found in high concentrations within the cell membrane of cells, since they are component lipids that make up sphingomyelin, one of the major lipids in the lipid bilayer.
As a bioactive lipid, ceramide has been implicated in a variety of physiological functions including apoptosis, cell growth arrest, differentiation, cell senescence, cell migration and adhesion. Roles for ceramide and its downstream metabolites have also been suggested in a number of pathological states including cancer, neurodegeneration, Diabetes, microbial pathogenesis, Fettleibigkeit, und Entzündung.

Funktion

  1. Barrier Function: The relationship between skin barrier function and skin lipids was studied.
  2. Adhesive Effect: Transamide binds to proteins on the cell surface through ester bonds, and this interconnection is known as a lipid-cell-protein envelope. The degree of adhesion between keratinocytes was determined by the content of ceramide in the cuticle of the epidermis. The decrease of ceramide content in the cuticle of the epidermis could reduce the adhesion between keratinocytes, resulting in dry, desquamated and scaly skin.
  3. Moisturizing Function: Ceramide has a strong ability to associate with water molecules and maintains skin moisture by forming a network in the stratum corneum.Therefore, ceramides have the function of retaining moisture in the skin.
  4. Anti-aging Effect: The use of ceramide can increase the content of ceramide in the cuticle of the epidermis and improve the condition of dry skin, desquamation and roughness.At the same time, ceramide can increase the thickness of cuticle, improve skin water holding capacity, Falten reduzieren, enhance skin elasticity, and delay skin aging.

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